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N-Nitroso apixaban open ring acid

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N-Nitroso apixaban open ring acid, >98%

IUPAC Name : 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl)(nitroso)amino)pentanoic acid

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C25H26N6O6
Mol. Weight :
506.52
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Apixaban, which is a highly selective, reversible Factor Xa inhibitor. Apixaban is used for the treatment and prevention of deep venous thrombosis, which involves the formation of blood clots in leg blood vessels.

References : Ding H. X. et al.: Bioorg. Med. Chem. 21(11), 2795-2825, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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