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N-Nitroso articaine

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N-Nitroso articaine, >98%

IUPAC Name : Methyl 4-methyl-3-(2-(nitroso(propyl)amino)propanamido)thiophene-2-carboxylate

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C13H19N3O4S
Mol. Weight :
313.37
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Articaine, which is a selective inhibitor of voltage-gated sodium channels (such as rNav1.4, hNav1.7, and rNav1.8). Articaine can be used in the study of dental local anesthesia and inflammatory-related diseases, such as acute kidney injury.

References : Wang G. K. et al.: J. Membr Biol., 229(1), 1-9, 2009; Zhao G. et al.: J. Biochem Mol Toxicol., 34(10), e22554, 2020; Rodrigues da Silva G. H. et al.: Sci Rep. 10(1), 19733, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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