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N-Nitroso bictegravir dibenzyl analog standard

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N-Nitroso bictegravir dibenzyl analog standard, >98%

IUPAC Name : (2R,5S,13aR)-N-(2,6-Difluoro-4-(nitroso(2,4,6-trifluorobenzyl)amino)benzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C28H22F5N5O6
Mol. Weight :
619.51
Appearance :
Pale beige solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Bictegravir, which is a novel, potent inhibitor of HIV-1 integrase for HIV-1 treatment in adults and children (with specific weight requirements) and as post-exposure prophylaxis (PEP).

References : Poyurovsky M. et al.: Int Clin Psychopharmacol., 20(2), 101, 2005; Gbahou F. et al.: J. Pharmacol Exp Ther., 334(3), 945, 2010; Tang K.T. et al.: Int Immunopharmacol., 39, 236, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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