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N-Nitroso desmethyl azelastine

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N-Nitroso desmethyl azelastine, >98%

IUPAC Name : 4-(4-Chlorobenzyl)-2-(1-nitrosoazepan-4-yl)phthalazin-1(2H)-one

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C21H21ClN4O2
Mol. Weight :
396.88
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Azelastine, an antihistamine medication. Azelastine is a potent and selective histamine H1 antagonist, and it can be used for research on allergic rhinitis, asthma, diabetic hyperlipidaemia, and SARS-CoV-2.

References : Craig L. F.: Expert Rev Clin Immunol., 1(2), 191-201, 2005; Mohamed M. E. et al.: Arch Physiol Biochem., 1-8, 2020; Carlos D. Z. et al.: Pharmacol Res Perspect., 7(6), e00531, 2019; Li Y. et al.: Acta Pharmacol Sin., 1-7, 2020; Shao-Cheng L. et al.: Eur Arch Otorhinolaryngol., 274(2), 845-853, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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