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N-Nitroso desmethyl bedaquiline

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N-Nitroso desmethyl bedaquiline, >98%

IUPAC Name : N-((3S,4R)-4-(6-Bromo-2-methoxyquinolin-3-yl)-3-hydroxy-3-(naphthalen-1-yl)-4-phenylbutyl)-N-methylnitrous amide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C31H28BrN3O3
Mol. Weight :
570.49
Appearance :
Brown solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Bedaquiline, which is an orally administered diarylquinoline. Bedaquiline serves as a bactericidal agent against mycobacteria by inhibiting proton-translocating ATP synthase.

References : Palmer D. B. et al.: J. Med. Chem., 58(7), 3036-3059, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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