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N-Nitroso desmethyl benztropine

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N-Nitroso desmethyl benztropine, >98%

IUPAC Name : (1R,5S)-3-(Benzhydryloxy)-8-nitroso-8-azabicyclo[3.2.1]octane

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C20H22N2O2
Mol. Weight :
322.41
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Benztropine, which is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine is also a human D2 dopamine receptor allosteric antagonist. Benztropine also has anti-cancer stem cells effects.

References : Jihong C. et al.: Oncotarget., 8(1), 1007-1022, 2017; Santosh S. K. et al.: Bioorg Med Chem., 14(11), 3625-34, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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