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N-Nitroso desmethyl neratinib

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N-Nitroso desmethyl neratinib, >98%

IUPAC Name : (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(methyl(nitroso)amino)but-2-enamide

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C29H26ClN7O4
Mol. Weight :
572.02
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Neratinib, which is a highly selective HER2 and EGFR inhibitor. Neratinib is an anticancer medication used for the treatment of breast cancer.

References : Rabindran S. K. et al.: Cancer Res., 64(11), 3958-3965, 2004; Yoshioka T. et al.: Cancer Sci., 109(4), 1166-1176, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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