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N-Nitroso desmethyl promethazine

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N-Nitroso desmethyl promethazine, >98%

CAS No. : [94511-44-1]

IUPAC Name : N-(1-(10H-Phenothiazin-10-yl)propan-2-yl)-N-methylnitrous amide

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Chemical Properites
Mol. Formula :
C16H17N3OS
Mol. Weight :
299.39
Appearance :
Pale pink solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Promethazine, which is a potent histamine H1 receptor antagonist, used as a sedative and antiallergic medication.

References : Edge W. et al.: J. Pharm. Pharmacol., 5, 279, 1953; Huang et al.: J. Pharm. Sci., 59, 772, 1970; Shearer C. M. et al.: Anal. Profiles Drug Subs., 5, 429, 1976.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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