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N-Nitroso desmethyl rizatriptan

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N-Nitroso desmethyl rizatriptan, >98%

IUPAC Name : N-(2-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1H-indol-3-yl)ethyl)-N-methylnitrous amide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C14H16N6O
Mol. Weight :
284.32
Appearance :
Brown gummy material
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Rizatriptan, which is an agonist at serotonin 5-HT1B and 5-HT1D receptors. It is used to treat acute migraine attacks.

References : Williamson D. J. et al.: Br. J. Pharmacol., 133(7), 1029-1034, 2001; Williamson D. J. et al.: Eur J. Pharmacol., 328(1), 61-64, 1997; Yao G. et al.: Neural Regen Res., 7(2), 131-135, 2012; Wang X. et al.: Brain Res., 1367, 340-346, 2011; Dong Z. et al.: Brain Res., 1368, 151-158, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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