N-Nitroso desmethyl vazegepant

SL-11850

N-Nitroso desmethyl vazegepant, >98%

Synonyms : N-Nitroso desmethyl zavegepant

IUPAC Name : (R)-N-(3-(7-Methyl-1H-indazol-5-yl)-1-(4-(1-nitrosopiperidin-4-yl)piperazin-1-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a nitrosamine impurity of Vazegepant, which is an orally active CGRP receptor antagonist used in migraine research and can also be given intranasally. CGRP plays a key role in migraine pathophysiology.

References : Moreno-Ajona D. et al.: Curr Opin Neurol., 33(3), 309-315, 2020; Gene M. D. et al.: Med Chem., 63(13), 6600-6623, 2020; Capi M. et al.: Springer International Publishing, 67-72, 2022; Jessica Barreto R. D. S. et al.: Eur. J. Pharmacol., 922, 174902, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.