N-Nitroso Ibrutinib dimer 1

SL-9508

N-Nitroso Ibrutinib dimer 1, >98%

IUPAC Name : N-(1-((R)-1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(3-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)nitrous amide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a nitrosamine impurity of Ibrutinib, which is a selective, irreversible BTK inhibitor. Ibrutinib is used to treat adults with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).

References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107(29), 13075-13080, 2010; Herman S. E. et al.: Blood. 117(23), 6287-6296, 2011; Chang B. Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7(1), 466, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.