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N-Nitroso imatinib-d3

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N-Nitroso imatinib-d3, >98%

IUPAC Name : N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-(methyl-d3)piperazin-1-yl)methyl)benzamide

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C29H27D3N8O2
Mol. Weight :
525.63
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version nitrosamine impurity of Imatinib, which is a tyrosine kinases inhibitor. It is used to treat certain types of leukaemia, which is a cancer that originates in white blood cells, as well as other forms of cancer.

References : Heinrich M. C. et al.: Blood. 96(3), 925-932, 2000; Guida T. et al.: Clin Cancer Res. 13(11), 3363-3369, 2007; Okuda K. et al.: Blood. 97(8), 2440-2448, 2001; Yao J. C. et al.: Clin Cancer Res. 13(1), 234-240, 2007; Sun X. C. et al.: World J. Gastroenterol. 19(15), 2340-2347, 2013; Yildiz C. et al.: Eur J. Obstet Gynecol Reprod Biol. 197, 159-163, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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