N-Nitroso-N-desmethyl nintedanib

SL-8551

N-Nitroso-N-desmethyl nintedanib, >98%

IUPAC Name : Methyl (Z)-3-(((4-(N-methyl-2-(4-nitrosopiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a nitrosamine impurity of Nintedanib, which is a multi-target tyrosine kinase inhibitor that works by competitively binding to the intracellular adenosine triphosphate (ATP) binding site on growth factor receptors, including vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptors (PDGFR), and fibroblast growth factor receptors (FGFR). Nintedanib is used to treat idiopathic pulmonary fibrosis.

References : Flick C. A et al.: Bioorg. Med. Chem., 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.