N-Nitroso N-desmethyl osimertinib 1

SL-9712

N-Nitroso N-desmethyl osimertinib 1, >98%

IUPAC Name : N-(4-Methoxy-2-(methyl(2-(methyl(nitroso)amino)ethyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a nitrosamine impurity of Osimertinib, which is a third-generation epidermal growth factor receptor (EGFR) inhibitor, used to treat non-small-cell lung carcinomas with a specific mutation.

References : Finlay M. R. et al. J. Med Chem., 57(20), 8249-8267, 2014; Cross D. A. et al.: Cancer Discov., 4(9), 1046-1061, 2014; Eberlein C. A. et al.: Cancer Res., 75(12), 2489-2500, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.