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N-Nitroso-N-desmethyl tapentadol

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N-Nitroso-N-desmethyl tapentadol, >98%

IUPAC Name : N-((2R,3R)-3-(3-Hydroxyphenyl)-2-methylpentyl)-N-methylnitrous amide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C13H20N2O2
Mol. Weight :
236.32
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Tapentadol, which is a novel, centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical and clinical models of pain relief.

References : Liu K. K-C. et al.: Bioorg. Med. Chem., 19(3), 1136-1154, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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