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N-Nitroso nortriptyline

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N-Nitroso nortriptyline, >98%

CAS No. : [55855-42-0]

IUPAC Name : N-(3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl)-N-methylnitrous amide

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Chemical Properites
Mol. Formula :
C19H20N2O
Mol. Weight :
292.38
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Nortriptyline, which is the main active metabolite of Amitriptyline. It is a tricyclic antidepressant. Nortriptyline is a potent autophagy inhibitor and has anticancer effects.

References : Petrosyan E. et al.: Int J. Cancer 151(2), 167-180, 2022; Sheau-Yun Y. et al.: Eur J Pharmacol., 761, 309-20, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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