N-Nitroso of timolol EP impurity E

SL-9011

N-Nitroso of timolol EP impurity E, >98%

IUPAC Name : (S,Z)-4-((1-(tert-Butyl(nitroso)amino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a nitrosamine impurity of Timolol, which is a non-selective, beta-adrenergic receptor antagonist. Timolol is used to treat increased pressure inside the eye such as in ocular hypertension and glaucoma.

References : Hall R. A. et al.: Arch Int Pharmacodyn Ther., 213(2), 251-263, 1975; Phan T. M. et al.: J. Ocul. Pharmacol., 7(3), 243-252, 1991; Wang T. et al.: Br. J. Clin. Pharmacol., 42(2), 217-223, 1996; Hirooka K. et al.: Exp Eye Res., 70(5), 611-621, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.