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N-Nitroso quinapril

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N-Nitroso quinapril, >98%

CAS No. : [2922985-13-3]

IUPAC Name : (S)-2-(N-((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)-N-nitroso-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

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Chemical Properites
Mol. Formula :
C25H29N3O6
Mol. Weight :
467.52
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Quinapril, which is an angiotensin converting enzyme (ACE) inhibitor. Quinapril is used to treat high blood pressure and heart failure.

References : Song J. C. et al.: Clin Pharmacokinet., 41(3), 207-24, 2002; Culy C. R. et al.: Drugs 62(2), 339-85, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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