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N-Nitroso ramipril

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N-Nitroso ramipril, >98%

IUPAC Name : (2S,3aS,6aS)-1-(N-((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)-N-nitroso-L-alanyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C23H31N3O6
Mol. Weight :
445.52
Appearance :
Off-white solid (hygroscopic)
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Ramipril, which is an angiotensin-converting enzyme (ACE) inhibitor. It is used for treating high blood pressure, heart failure, and diabetic kidney disease, as well as for preventing cardiovascular disease in individuals at high risk.

References : Stevens B. R. et al.: Comp Biochem Physiol C, 91(2), 493-497, 1988; Kohlstedt K. et al.: Circ Res, 94(1), 60-67, 2004; Ceconi C. et al.: Cardiovasc Drugs Ther, 21(6), 423-429, 2007; Raasch W. et al.: J. Hypertens, 22(3), 611-618, 2004; Cushman D. W. et al.: Br. J. Clin Pharmacol, 28, 115S-131S, 1989; Toffoli B. et al.: Mol Cell Endocrinol, 331(1), 136-142, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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