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N-Nitroso ranolazine impurity A

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N-Nitroso ranolazine impurity A, >98%

Synonyms : N-Nitroso ranolazine impurity 20

IUPAC Name : 1-(2-Methoxyphenoxy)-3-(4-nitrosopiperazin-1-yl)propan-2-ol

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Chemical Properites
Mol. Formula :
C14H21N3O4
Mol. Weight :
295.34
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Ranolazine, which is a calcium uptake inhibitor via the sodium/calcium channel. Ranolazine is used to treat chronic angina.

References : Undrovinas A. I. et al.: J. Cardiovasc Electrophysiol., 17 Suppl 1, S169-S177, 2006; Song Y. et al. J. Cardiovasc Pharmacol., 44(2), 192-199, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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