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N-Nitroso sacubitril KSM

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N-Nitroso sacubitril KSM, >98%

IUPAC Name : (2S,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)(nitroso)amino)-2-methylpentanoic acid

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C23H28N2O5
Mol. Weight :
412.49
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Sacubitril, which is a potent NEP inhibitor. Sacubitril is a key component of the heart failure medication LCZ696.

References : Ksander G. M. et al.: J. Med. Chem., 38(10), 1689-700, 1995; Voors A. A. et al.: Expert Opin Investig Drugs 22(8), 1041-1047, 2013; von Lueder T. G. et al. Circ Heart Fail. 8(1), 71-78, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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