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N-Nitroso tamsulosin-d4

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N-Nitroso tamsulosin-d4, >98%

IUPAC Name : (R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl-1,1,2,2-d4)(nitroso)amino)propyl)-2-methoxybenzenesulfonamide

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C20H23D4N3O6S
Mol. Weight :
441.54
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine deuterium labelled version impurity of Tamsulosin, which is an orally administered antagonist of the α1-adrenergic receptor that induces apoptosis. Tamsulosin is commonly studied for its effects on prostatic hyperplasia. Additionally, in animal models, Tamsulosin has been shown to reduce the growth of abdominal aortic aneurysms and suppress inflammation.

References : Chapple C. et al.: World J. Urol., 19(6), 397-404, 2002; Rak A. et al.: Bioorg Med Chem., 24(21), 5582-5591, 2016; Sun L. et al.: Bioengineered., 12(1), 5184-5194, 2021; Ida Y. et al.: Bioengineering (Basel). 9(10), 556, 2022; Youm Y. H. et al.: Journal of the Korean Continence Society,10(2), 132-139, 2006; Holanda V. A. D. et al.: Brain Res Bull., 178, 29-36, 2022; Kim S. E. et al.: Int. Neurourol J. 16(1), 13-22, 2012; Alabdali H. H. et al.: Bulletin of Pharmaceutical Sciences 46(1), 633-645, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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