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N-Nitroso terbinafine EP impurity A

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N-Nitroso terbinafine EP impurity A, >98%

CAS No. : [296760-88-8]

IUPAC Name : N-Methyl-N-(naphthalen-1-ylmethyl)nitrous amide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG95.00
In Stock  Estimated to ship on 20 September 2026
10MG135.00
In Stock  Estimated to ship on 20 September 2026
25MG275.00
In Stock  Estimated to ship on 20 September 2026
50MG525.00
In Stock  Estimated to ship on 20 September 2026
100MG955.00
In Stock  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C12H12N2O
Mol. Weight :
200.24
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Terbinafin, which is an orally active and potent antifungal agent. Terbinafin is a non-competitive inhibitor of squalene epoxidase from Candida (Ki = 30 nM). It also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. This compound contains an Alkyne group and can act as a click chemistry reagent, undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.

References : Ryder N. S. et al.: Br. J. Dermatol.,126 Suppl 39, 2-7, 1992; Mieth H. et al.: Clin Exp Dermatol.,14(2), 104-7, 1989.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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