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N-Nitroso trandolapril

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N-Nitroso trandolapril, >98%

IUPAC Name : (2S,3aR,7aS)-1-(N-((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)-N-nitroso-L-alanyl)octahydro-1H-indole-2-carboxylic acid

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C24H33N3O6
Mol. Weight :
459.54
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI).

References : Peters D. C. et al.: Drugs 56(5), 871-93, 1998; Tan X. et al.: Kidney Int., 76(12), 1248-57, 2009; Koffi I. et al.: Eur J. Pharmacol., 361(1), 51-60, 1998; Chobanian A. V. et al.: Hypertension 20(4), 473-477, 1992.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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