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N-Nitroso trimetazidine-d9 hydrochloride

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N-Nitroso trimetazidine-d9 hydrochloride, >98%

IUPAC Name : 1-Nitroso-4-(2,3,4-tris(methoxy-d3)benzyl)piperazine hydrochloride

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C14H12D9N3O4 • HCl
Mol. Weight :
340.85
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
H2O
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium-labelled version nitrosamine impurity of Trimetazidine, which is an anti-ischemic (anti-anginal) metabolic agent that improves myocardial glucose utilization by inhibiting long-chain 3-ketoacyl CoA thiolase activity, resulting in reduced fatty acid oxidation and increased glucose oxidation.

References : Kantor P. F. et al.: Circ Res. 86(5), 580-588, 2000; Liu Z. et al.: Metabolism. 65(3), 122-130, 2016; Yang Q. et al.: Int. J. Clin Exp Pathol. 8(4), 3735-3741, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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