N-Nitroso upadacitinib

SL-9078

N-Nitroso upadacitinib, >98%

Synonyms : Upadacitinib nitroso impurity 2

IUPAC Name : (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-nitroso-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a nitrosamine impurity of Upadacitinib, which is a potent and selective Janus kinase (JAK) 1 inhibitor. Upadacitinib is being developed for the treatment of several autoimmune disorders.

References : Genovese M. C. et al.: Arthritis Rheumatol., 68(12), 2857-2866, 2016; Kremer J. M. et al.: Arthritis Rheumatol., 68(12), 2867-2877, 2016; Mohamed M. F. et al.: Clin Pharmacokinet., 55(12), 1547-1558, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.