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N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxamide

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SI-4839

N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxamide, >98% (HPLC)

CAS No. : [2230065-16-2]

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Chemical Properites
Mol. Formula :
C26H29N5O
Mol. Weight :
427.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is second generation analog of SB-269652 and have distinct pharmacological properties. A negative allosteric modulator of the dopamineD2 receptor.

References : Shonberg J. et al.: J. Med. Chem., 58(13), 5287-5307, 2015; Kopinathan A. et al.: J. Med. Chem., 62(1), 371-377, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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