N6-Acryloyl ibrutinib

SL-3356

N6-Acryloyl ibrutinib, >98%

CAS No. : [2031255-27-1]

IUPAC Name : (R)-N-(1-(1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)acrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
10MG	120.00		Back Order	Estimated to ship on 04 October 2026
25MG	250.00		Back Order	Estimated to ship on 04 October 2026
50MG	480.00		Back Order	Estimated to ship on 04 October 2026
100MG	880.00		Back Order	Estimated to ship on 04 October 2026

Applications : N6-Acryloyl ibrutinib is an impurity of Ibrutinib, which is a selective, irreversible Bruton's tyrosine kinase (Btk) inhibitor, used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia.

References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107(29), 13075-13080,2010; Herman S. E. et al.: Blood 117(23), 6287-6296, 2011; Chang B. Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7(1), 466, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.