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Naporafenib

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SI-5830

Naporafenib, >98% (HPLC)

CAS No. : [1800398-38-2]

Synonyms : LXH254

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Chemical Properites
Mol. Formula :
C25H25F3N4O4
Mol. Weight :
502.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Naporafenib is a type II ATP-competitive inhibitor that inhibits both B- and CRAF kinase activities at picomolar concentrations with a high degree of selectivity against a panel of 456 human kinases and in cell-based assays.

References : Stuart D. D. et al. AACR Cancer Res., 78(13 Suppl), Abstract nr DDT01-04, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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