Naquotinib mesylate

SI-7843

Naquotinib mesylate, >98% (HPLC)

CAS No. : [1448237-05-5]

Synonyms : ASP-8273 mesylate

IUPAC Name : (R)-5-((1-Acryloylpyrrolidin-3-yl)oxy)-6-ethyl-3-((4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrazine-2-carboxamide methanesulfonate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Naquotinib mesylate is a third‑generation, irreversible EGFR inhibitor that preferentially targets mutant EGFR variants, demonstrating IC₅₀ values of 8–33 nM compared with 230 nM for wild‑type EGFR. This mutant‑selective profile supports its use in studies of EGFR‑driven malignancies.

References : Sakagami H. et al.: Cancer Res.,74(19 Suppl), Abstract nr 1728, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.