NB-360

SI-2662

NB-360, >98% (HPLC)

CAS No. : [1262857-73-7]

MDL No. : 1262855-97-9 (HCl) 1416433-41-4 (xHCl)

IUPAC Name : N-(3-((3R,6R)-5-Amino-3,6-dimethyl-6-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl)-4-fluorophenyl)-5-cyano-3-methylpicolinamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: NB-360 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us atsales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : NB-360 is a potent and brain penetrable BACE-1 inhibitor. It shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.

References : Zhu K. et al.: Biol Psychiatry 83(5), 428-437,2018; Schelle J. et al.: Alzheimers Dement.,13(6), 701-709, 2017; Beckmann N. et al.: Neurobiol Aging., 45, 50-60, 2016; Neumann U. et al.: Mol Neurodegener., 10, 44, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.