NBI-12i

SI-7268

NBI-12i, >98% (HPLC)

IUPAC Name : Ethyl (1S,2S)-2-(4-((R)-2-(3-aminopropanamido)-3-(2,4-dichlorophenyl)propanoyl)piperazin-1-yl)cyclohexane-1-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : NBI‑121i is a small‑molecule MC4R antagonist demonstrating robust efficacy in preclinical models of melanocortin‑driven metabolic and CNS pathways. The scaffold supports high potency, CNS‑relevant exposure, and a drug‑like PK profile, positioning NBI‑121i as a promising lead for further development in MC4R‑modulated disorders.

References : Cheung W. W. et al.: J. Am. Soc. Nephrol., 18(9), 2517-24, 2007; Markison S. et al.: Endocrinology, 146(6), 2766-73, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.