ND-2158

SI-6347

ND-2158, >98% (HPLC)

CAS No. : [1388896-07-8]

IUPAC Name : (S)-2-Hydroxy-3-((R)-4-(((1r,4R)-4-morpholinocyclohexyl)oxy)-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-5-yl)propanamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : ND‑2158 selectively inhibits IRAK4 at low‑nanomolar potency and blocks downstream inflammatory signaling. It reduces TNF production in human WBCs, improves arthritis and gout outcomes in mouse models, and shows antitumor effects in vivo, making it valuable for probing IRAK4‑dependent immune and cancer biology.

References : Kelly P. N. et al.: J. Exp. Med., 212(13), 2189-2201, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.