NDT-30805

SI-7454

NDT-30805, >98% (HPLC)

IUPAC Name : 2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : NDT‑30805 is a triazolopyrimidinone derivative that selectively inhibits NLRP3 inflammasome activation, potently reducing IL‑1β secretion in PBMCs with an IC₅₀ of 0.013 µM. Its pharmacological profile makes it a valuable tool for investigating NLRP3‑mediated inflammation and innate immune pathways.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.