Neflamapimod

SI-7855

Neflamapimod, >98% (HPLC)

CAS No. : [209410-46-8]

Synonyms : VX-745

IUPAC Name : 5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Neflamapimod is a potent and selective p38α MAPK inhibitor with excellent CNS penetration, inhibiting p38α at 10 nM and p38β at 220 nM. Its selective targeting of p38α underlies its pronounced anti‑inflammatory effects.

References : Duffy J. P. et al.: ACS Med. Chem. Lett., 2(10), 758-63, 2011; McGuire V. A. et al.: Mol Cell. Biol., 33(21), 4152-65, 2013; Alam J. J. J. Alzheimers Dis., 48(1), 219-27, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.