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Nemiralisib

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SI-5155

Nemiralisib, >98% (HPLC)

CAS No. : [1254036-71-9]

MDL No. : MFCD28128611

Synonyms : GSK-2269557

IUPAC Name : 2-(6-(1H-Indol-4-yl)-1H-indazol-4-yl)-5-((4-isopropylpiperazin-1-yl)methyl)oxazole

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Chemical Properites
Mol. Formula :
C26H28N6O
Mol. Weight :
440.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Nemiralisib is a potent and highly selective PI3Kδ inhibitor with a pKi of 9.9. It is being developed for the treatment of inflammatory airways disease.

References : Down K. et al.: J. Med Chem., 58(18), 7381-99, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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