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Netarsudil mesylate

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SI-5462

Netarsudil mesylate, >98% (HPLC)

CAS No. : [1422144-42-0]

MDL No. : MFCD29472224

Synonyms : AR-13324 mesylate

IUPAC Name : (S)-4-(3-Amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate mesylate

Price And Availability
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10MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
We accept
Note: Netarsudil mesylate is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C28H27N3O3 . 2CH3SO2OH
Mol. Weight :
645.74
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Netarsudil mesylate is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is currently in clinical trials for the treatment of glaucoma and ocular hypertension.

References : Sturdivant J. M. et al.: Bioorg Med Chem Lett., 26(10), 2475-80, 2016; Li G. et al.: Eur J Pharmacol., 787, 20-31, 2016; Ren R. et al.: Invest Ophthalmol Vis Sci., 57(14), 6197-6209, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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