NIBR-189

SI-7429

NIBR-189, >98% (HPLC)

CAS No. : [1599432-08-2]

IUPAC Name : (E)-3-(4-Bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : NIBR-189 inhibits EBI2 with low‑nanomolar potency in both human (IC₅₀ = 11 nM) and mouse (IC₅₀ = 16 nM) systems. By blocking EBI2‑dependent chemotactic and immune‑signaling pathways, it serves as an important probe compound for studying autoimmune and inflammatory disorders.

References : Gessier F. et al.: J. Med. Chem., 57(8), 3358-68, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.