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NIBR-51

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SI-7426

NIBR-51, >98% (HPLC)

CAS No. : [287917-50-4]

IUPAC Name : 4-Chloro-N-(2,4-dichlorobenzyl)-N-(pyridin-3-ylmethyl)benzenesulfonamide

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Chemical Properites
Mol. Formula :
C19H15Cl3N2O2S
Mol. Weight :
441.75
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : NIBR‑51 is a selective GPR183 (EBI2) antagonist. It blocks GPR183‑mediated signaling with high potency and is used as a tool compound to study immune regulation, B‑cell positioning, and inflammatory disease mechanisms linked to GPR183 activity.

References : Gessier F. et al.: J. Med. Chem., 57(8), 3358-3368, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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