Nifetepimine

SI-6432

Nifetepimine, >98% (HPLC)

CAS No. : [110448-29-8]

IUPAC Name : Ethyl 6-methyl-4-(3-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Nifetepimine is a potent MEK/ERK pathway inhibitor showing strong anti‑proliferative activity in triple‑negative breast cancer (TNBC) models. By blocking MEK‑driven ERK phosphorylation, it suppresses tumor cell growth, survival, and metastatic signaling, making it a useful tool compound for studying MAPK‑dependent TNBC biology and evaluating MEK/ERK‑targeted therapeutic strategies.

References : Liao M. et al.: J. Med. Chem., 64(5), 2382-2418, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.