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CAS No. : [2119583-24-1]
Synonyms : 4-Desmethyl-4-ethylimidazolyl nilotinib
IUPAC Name : N-(3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 10MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 25MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 50MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 250MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C29H24F3N7O | Mol. Weight : 543.54 |
Appearance : Solid | Melting Point : Not available |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is an impurity of Nilotinib (Nilotinib EP impurity F), which is a selective Bcr-Abl tyrosine kinase inhibitor, for the potential treatment of various leukemias, including chronic myeloid leukemia (CML).
References : Weisberg E. et al. Blood, 109(5), 2112-2120, 2007; Liu Y. et al.: J. Hepatol, 55(3), 612-625, 2011; Hochhaus A. et al.: Cell Cycle, 10(2), 250-260, 2011; Ammoun S. et al.: Neuro Oncol., 13(7), 759-766, 2011; Rhee C. K. et al.: Respiration., 82(3), 273-287, 2011; Weisberg E. et al. Cancer Cell, 7(2), 129-141, 2005.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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