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Nilotinib impurity 10

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SL-3609

Nilotinib impurity 10, >98%

CAS No. : [641571-13-3]

MDL No. : MFCD09998833

IUPAC Name : 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic acid

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G215.00
Back Order  Estimated to ship on 04 October 2026
5G695.00
Back Order  Estimated to ship on 04 October 2026
10G1155.00
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C12H9F3N2O2
Mol. Weight :
270.21
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Nilotinib (Nilotinib impurity 10), which is a selective Bcr-Abl tyrosine kinase inhibitor, for the potential treatment of various leukemias, including chronic myeloid leukemia (CML).

References : Weisberg E. et al. Blood, 109(5), 2112-2120, 2007; Liu Y. et al.: J. Hepatol, 55(3), 612-625, 2011; Hochhaus A. et al.: Cell Cycle, 10(2), 250-260, 2011; Ammoun S. et al.: Neuro Oncol., 13(7), 759-766, 2011; Rhee C. K. et al.: Respiration., 82(3), 273-287, 2011; Weisberg E. et al. Cancer Cell, 7(2), 129-141, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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