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Nilotinib impurity 11

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Nilotinib impurity 11, >98%

CAS No. : [916975-92-3]

MDL No. : MFCD18800877

IUPAC Name : 4-Methyl-1-(3-nitro-5-(trifluoromethyl)phenyl)-1H-imidazole

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G655.00
In Stock  Estimated to ship on 20 September 2026
5G1855.00
In Stock  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C11H8F3N3O2
Mol. Weight :
271.20
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Nilotinib (Nilotinib impurity 11), which is a selective Bcr-Abl tyrosine kinase inhibitor, for the potential treatment of various leukemias, including chronic myeloid leukemia (CML).

References : Weisberg E. et al. Blood, 109(5), 2112-2120, 2007; Liu Y. et al.: J. Hepatol, 55(3), 612-625, 2011; Hochhaus A. et al.: Cell Cycle, 10(2), 250-260, 2011; Ammoun S. et al.: Neuro Oncol., 13(7), 759-766, 2011; Rhee C. K. et al.: Respiration., 82(3), 273-287, 2011; Weisberg E. et al. Cancer Cell, 7(2), 129-141, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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