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Nilotinib impurity 8

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SL-3607

Nilotinib impurity 8, >98%

CAS No. : [641571-12-2]

MDL No. : MFCD10000967

IUPAC Name : 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G395.00
Back Order  Estimated to ship on 04 October 2026
5G1395.00
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C12H8F3N3
Mol. Weight :
251.21
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Nilotinib (Nilotinib impurity 8), which is a selective Bcr-Abl tyrosine kinase inhibitor, for the potential treatment of various leukemias, including chronic myeloid leukemia (CML).

References : Weisberg E. et al. Blood, 109(5), 2112-2120, 2007; Liu Y. et al.: J. Hepatol, 55(3), 612-625, 2011; Hochhaus A. et al.: Cell Cycle, 10(2), 250-260, 2011; Ammoun S. et al.: Neuro Oncol., 13(7), 759-766, 2011; Rhee C. K. et al.: Respiration., 82(3), 273-287, 2011; Weisberg E. et al. Cancer Cell, 7(2), 129-141, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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