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Nilvadipine

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SI-6328

Nilvadipine, >98% (HPLC)

CAS No. : [75530-68-6]

Synonyms : FR-34235; FK-235

IUPAC Name : 5-Isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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Chemical Properites
Mol. Formula :
C19H19N3O6
Mol. Weight :
385.38
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Nilvadipine is a potent blocker of voltage‑dependent calcium channels, showing an IC50 near 0.1 nM. It is widely used to study calcium‑regulated vascular tone and neuronal signaling.

References : Nomoto A. et al.: Atherosclerosis., 72(2-3), 213-9, 1998; Nomoto A. et al.: Atherosclerosis., 64(2-3), 255-61, 1987; Sugawara H. et al.: Hypertens. Res., 19(4), 223-8, 1996; Yamazaki H. et al.: Invest. Ophthalmol. Vis. Sci., 43(4), 919-26, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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