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Nilvadipine-d4

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SI-6329

Nilvadipine-d4, >98% (HPLC)

Synonyms : FR-34235-d4; FK-235-d4

IUPAC Name : 5-Isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl-2,4,5,6-d4)-1,4-dihydropyridine-3,5-dicarboxylate

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C19H15D4N3O6
Mol. Weight :
389.4
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Nilvadipine‑d4 is a deuterium‑labeled version of Nilvadipine, which potently blocks voltage‑dependent calcium channels with an IC50 near 0.1 nM. The isotopic substitution enables applications in metabolic profiling and quantitative LC‑MS analyses.

References : Russak E. M. et al., Ann. Pharmacother., 53(2), 211-216, 2019; Nomoto A. et al.: Atherosclerosis. 72(2-3), 213-9, 1988; Nomoto A. et al.: Atherosclerosis, 64(2-3), 255-61, 1987; Sugawara H. et al.: Hypertens Res., 19(4), 223-8, 1996; Yamazaki H. et al.: Invest. Ophthalmol. Vis. Sci., 43(4), 919-26, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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