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SI-3535

Nintedanib, >98% (HPLC)

CAS No. : [656247-17-5]

MDL No. : MFCD11113419

Synonyms : Intedanib; Vargatef; BIBF 1120

IUPAC Name : (Z)-Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G40.00
Back Order  Estimated to ship on 04 October 2026
5G135.00
Back Order  Estimated to ship on 04 October 2026
25G455.00
Back Order  Estimated to ship on 04 October 2026
100G1195.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C31H33N5O4
Mol. Weight :
539.62
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.

References : Flick C. A et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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