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Nintedanib-d8

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SL-2733

Nintedanib-d8, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1624587-87-6]

Synonyms : Intedanib-d8; Vargatef-d8; BIBF 1120-d8

IUPAC Name : (Z)-Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate-d8

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Chemical Properites
Mol. Formula :
C31H25D8N5O4
Mol. Weight :
547.67
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
Methanol
For Laboratory research use only, not for drug, household or other uses.

Applications : Nintedanib-d8 is a deuterium labelled version of Nintedanib, which is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β. An antitumor agent.

References : Flick C. A et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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