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Nintedanib esylate

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SI-3536

Nintedanib esylate, >98% (HPLC)

CAS No. : [656247-18-6]

MDL No. : MFCD26142360

Synonyms : Intedanib esylate; Vargatef esylate; BIBF 1120 esylate

IUPAC Name : (Z)-Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate ethanesulfonate

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1G35.00
Back Order  Estimated to ship on 04 October 2026
5G135.00
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10G225.00
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25G455.00
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Chemical Properites
Mol. Formula :
C31H33N5O4 . EtSO3H
Mol. Weight :
649.76
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.

References : Flick C. A et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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