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Nirmatrelvir (R)-nitrile isomer

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Nirmatrelvir (R)-nitrile isomer, >98%

CAS No. : [2755812-41-8]

IUPAC Name : (1R,2S,5S)-N-((R)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C23H32F3N5O4
Mol. Weight :
499.54
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an (R)-nitrile isomer of Nirmatrelvir, which is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor. This can be used for COVID-19 research studies.

References : Koen V. et al.: Current Opinion in Virology 49, 41-51, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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